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KMID : 1059520170610060352
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Journal of the Korean Chemical Society
2017 Volume.61 No. 6 p.352 ~ p.358
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The Effect of Wettability and Protein Adsorption of Contact Lens by Alginic Acid
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Ko Na-Young
Lee Kyung-Mun
Lee Hyun-Mee
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Abstract
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The addition of alginic acid, a natural polysaccharide, to improve the wettability and the reduction of protein adsorption of hydrogel contact lenses. Hydrogel contact lenses were manufactured with various monomers such as 2-methacryloyloxyethyl phosphorylcholine (MPC) and NVP (N-Vinyl-2-pyrrolidone). Alginic acid was added by by the initial mixing method and the interpenetrating polymer networks(IPN) method. Properties of contact lens such as contact angle, oxygen permeability, and protein adsorption amount were evaluated. The oxygen permeability and wettability of the IPN-treated alginate samples were higher than those of the samples that were not treated with IPN. The physical properties were improved as the concentration of IPN-treated alginic acid increased. Protein adsorption decreased by the addition of alginic acid and further decreased with IPN. In particular, contact lenses containing MPC and NVP significantly decreased protein adsorption. Therefore, the effect of alginate on the functional improvement of contact lens was confirmed.
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KEYWORD
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Alginic acid, Wettability, Oxygen permeability, Protein adsorption, IPN
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